Flatiron RWE Data for Oncology (USA)

Database Contact Data

Flatiron Heath 
233 Spring Street
New York, NY 10013
USA
(Submit requests online at https://flatiron.com/contact/)

Alternate Contact

N/A

References of Studies Using/Describing Database

1. Rugo HS, Liu X, Li B, McRoy L, Chen C, Layman RM, Brufsky A. Real-world treatment patterns for palbociclib plus an aromatase inhibitor, or an aromatase inhibitor alone, for patients with metastatic breast cancer in the Flatiron Database. Int J Cancer. 2024 Feb 15;154(4):701-711.

2. Nicholson G, Carlson KB, Hernandez RK, Schenfeld J, Cadieux B, Henry D, De Sousa Barbosa VJ, Saad H. Treatment Patterns of Bone-targeting Agents Among Solid Tumor Patients With Bone Metastases: An Analysis of Electronic Health Record Data in the United States From 2014 to 2018. Am J Clin Oncol. 2024 Jan 11. doi: 10.1097/COC.0000000000001075. Epub ahead of print.

3. Castellanos EH, Wittmershaus BK, Chandwani S. Raising the Bar for Real-World Data in Oncology: Approaches to Quality Across Multiple Dimensions. JCO Clin Cancer Inform. 2024 Jan;8:e2300046.

4. Hantel A, Cernik C, Uno H, Walsh TP, Calip GS, DeAngelo DJ, Lathan CS, Abel GA. Sociodemographic associations with uptake of novel therapies for acute myeloid leukemia. Blood Cancer J. 2023 Dec 21;13(1):192.

5. Passamonti F, Lou Y, Chevli M, Abraham P. Real-world outcomes with fedratinib therapy in patients who discontinued ruxolitinib for primary myelofibrosis. Future Oncol. 2023 Nov 22. doi: 10.2217/fon-2022-1256.

6. Brufsky A, Liu X, Li B, McRoy L, Chen C, Layman RM, Rugo HS. Palbociclib Combined with an Aromatase Inhibitor in Patients with Breast Cancer with Lung or Liver Metastases in US Clinical Practice. Cancers (Basel). 2023 Nov 2;15(21):5268.

7. Rugo HS, Liu X, Li B, McRoy L, Chen C, Layman RM, Brufsky A. Real-World Effectiveness of Palbociclib Plus Aromatase Inhibitors in African American Patients With Metastatic Breast Cancer. Oncologist. 2023 Oct 3;28(10):866-874.  

8. Eyre TA, Hess LM, Sugihara T, He D, Khanal M, Pagel JM, Walgren RA, B Abada P, Konig H, Roeker LE, Mato A. Clinical outcomes among patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) who received treatment with a covalent BTK and BCL2 inhibitor in the United States: a real-world database study. Leuk Lymphoma. 2023 May;64(5):1005-1016.

9. Zeidan AM, Pollyea DA, Borate U, Vasconcelos A, Potluri R, Rotter D, Kiendrebeogo Z, Gaugler L, Prebet T, Strocchia M, Bonifacio G, Chen C. Venetoclax plus azacitidine compared with intensive chemotherapy as induction for patients with acute myeloid leukemia: retrospective analysis of an electronic medical record database in the United States. Ann Hematol. 2023 Apr;102(4):749-754.

10. Rugo HS, Raskina K, Schrock AB, Madison RW, Graf RP, Sokol ES, Sivakumar S, Lee JK, Fisher V, Oxnard GR, Tukachinsky H. Biology and Targetability of the Extended Spectrum of PIK3CA Mutations Detected in Breast Carcinoma. Clin Cancer Res. 2023 Mar 14;29(6):1056-1067.

8/3/20: Harvard Pilgrim Health Care is the newest profile added

HPHC is a non-profit regional health plan providing medical insurance/administering insurance benefits for >2.7 million members; over 80% of members also have full pharmacy coverage. The HPHC provider network comprises nearly 9,000 primary care providers and 18,000 specialist physicians who practice in a broad range of settings. Enrollment and administrative claims data are available for HPHC members from 2000 to present. Linked electronic medical record data are available for about 13% of the HPHC member population.

Harvard Pilgrim Health Care (USA)

Database Contact Data

Garett Kopczynski
Manager of Administration
Department of Population Medicine
Harvard Medical School/Harvard Pilgrim Health Care Institute
401 Park Drive Suite 401
Boston, MA 02215
USA
Email: garett_kopczynski@harvardpilgrim.org
Phone: +1 617-867-4314

Alternate Contact

Kim Lane at
Harvard Medical School/Harvard Pilgrim Health Care Institute
401 Park Drive Suite 401
Boston, MA 02215
USA
Email: Kimberly.lane@channing.harvard.edu

References of Studies Using/Describing Database

1. Klompmaker JO, Laden F, James P, Sabath MB, Wu X, Schwartz J, Dominici F, Zanobetti A, Hart JE. Effects of long-term average temperature on cardiovascular disease hospitalizations in an American elderly population. Environ Res. 2023 Jan 1;216(Pt 3):114684.

2. Kamidani S, Panagiotakopoulos L, Licata C, Daley MF, Yih WK, Zerbo O, Tseng HF, DeSilva MB, Nelson JC, Groom HC, Williams JTB, Hambidge SJ, Donahue JG, Belay ED, Weintraub ES. Kawasaki Disease Following the 13-valent Pneumococcal Conjugate Vaccine and Rotavirus Vaccines. Pediatrics. 2022 Dec 1;150(6):e2022058789. 

3. Pak TR, Rhee C, Klompas M. Timing and Spectrum of Antibiotic Treatment for Suspected Sepsis and Septic Shock: Why so Controversial? Infect Dis Clin North Am. 2022 Dec;36(4):719-733.

4. Lin PI, Cardenas A, Rifas-Shiman SL, Zota AR, Hivert MF, Aris IM, Sanders AP. Non-essential and essential trace element mixtures and kidney function in early pregnancy–A cross-sectional analysis in project viva. Environmental Research. 2022 Nov 17:114846.

5. Hecker J, Prokopenko D, Moll M, Lee S, Kim W, Qiao D, Voorhies K, Kim W, Vansteelandt S, Hobbs BD, Cho MH. A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables. PLoS genetics. 2022 Nov 16;18(11):e1010464.

6. Wilson AC, Bon JM, Mason S, Diaz AA, Lutz SM, Estepar RSJ, Kinney GL, Hokanson JE, Rennard SI, Casaburi R, Bhatt SP, Irvin MR, Hersh CP, Dransfield MT, Washko GR, Regan EA, McDonald ML. Increased chest CT derived bone and muscle measures capture markers of improved morbidity and mortality in COPD. Respir Res. 2022 Nov 15;23(1):311.

7. Boehmer TK, Koumans EH, Skillen EL, Kappelman MD, Carton TW, Patel A, August EM, Bernstein R, Denson JL, Draper C, Gundlapalli AV, Paranjape A, Puro J, Rao P, Siegel DA, Trick WE, Walker CL, Block JP. Racial and Ethnic Disparities in Outpatient Treatment of COVID-19 - United States, January-July 2022. MMWR Morb Mortal Wkly Rep. 2022 Oct 28;71(43):1359-1365.

8. Nam YH, Willis SJ, Mendelsohn AB, Forrow S, Gessner BD, Stark JH, Brown JS, Pugh S. Healthcare claims-based Lyme disease case-finding algorithms in the United States: A systematic literature review. PLoS One. 2022 Oct 27;17(10):e0276299.

9. Smith HS, Sanchez CE, Maag R, Buentello A, Murdock DR, Metcalf GA, Hadley TD, Riconda DL, Boerwinkle E, Wehrens XHT, Ballantyne CM, Gibbs RA, McGuire AL, Pereira S. Patient and Clinician Perceptions of Precision Cardiology Care: Findings From the HeartCare Study. Circ Genom Precis Med. 2022 Oct 25:e003605.

10. Taschereau A, Desgagné V, Faleschini S, Guérin R, Allard C, Perron P, Hivert MF, Bouchard L. SERPINE1 DNA Methylation Levels Quantified in Blood Cells at Five Years of Age Are Associated with Adiposity and Plasma PAI-1 Levels at Five Years of Age. Int J Mol Sci. 2022 Oct 5;23(19):11833.

Rehman N, Portnoy J, Wu AC. Could Telemedicine Be Here to Stay? Understanding the Rapidly Changing Landscape of Telemedicine in Allergy and Immunology Practice. J Allergy Clin Immunol Pract. 2022 Oct;10(10):2550-2551.

7/2/20: Biobank details added to the Women’s Health Initiative profile.

See some new information in a profile? In addition to regularly updating data in the existing fields of profiles, we also add new elements. The Women’s Health Initiative for instance, now has valuable NEW information in the biobank category that may aide you in your search for the perfect database. Contact us for assistance with your next search or if you need help with a data landscaping project.

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