Cross Fact Health Insurance Claims Database (Japan) | B.R.I.D.G.E. TO DATA®, DGI, LLC

Summary

Coordinating Country

Japan

Region

Japan

Brief Database Description

The Cross Fact Health Insurance Claims Database of Japan is a longitudinal database containing employer-sponsored insurance claims. Specifically, Cross Fact has drug and diagnosis data with medical and pharmacy insurance claims for both outpatients and inpatients.

This database has data since the year 2010 on >7 million patients. It has excellent coverage including local (regional) areas of Japan (i.e., prefectures), with the additional ability to track treatment and medication(s) on a per-patient basis.

NOTE: Dental insurance claims are also included, but not organ transplant-related claims or patient comment fields.

Database Type

Longitudinal Population Database

- Drug and Diagnosis Data

- - Medical and Pharmacy Insurance Claims

- - - Outpatient and inpatient

(The Cross Fact Health Insurance Claims Database of Japan is a longitudinal database containing employer-sponsored insurance claims. Specifically, Cross Fact has drug and diagnosis data with medical and pharmacy insurance claims for both outpatients and inpatients.)

Database Source

Medical Insurance Claims

Frequency of Data Collection

Monthly

Frequency of Data Update

Monthly

Years Covered

2010 - Present

Most data are available since 2012, though some data are available starting 2010

Population Type

Insured

Health insurance societies for salaried workers

Patient Type

Inpatient and Outpatient

Date of Last Update

Ongoing

(The Cross Fact Health Insurance Claims Database is updated on an ongoing basis;
This profile was developed for the B.R.I.D.G.E. TO DATA site on October 14, 2022.)

Population Dynamics

Database Population Size

5 - 20 Million

(>7 Million)

Active Population Size

5 - 20 Million

(>7 Million)

Annual Change in Population

N/A

(Not applicable)

Sample Weights - Extrapolation Factors

Final Population Size

N/A

(Not applicable as data are still being collected)

Demographic Data

Age of Patients at Data Collection

Yes

(Month of Birth is recorded)

Approximate Percentage of Participants <18 years and those >65 years

< 18 years = 22%
> 65 years = 4%

Gender Data

Yes

Percentage of Males/Females

Males = 48%
Females = 52%

Ethnicity / Race Data

Geographic Location

Prefectures of Japan

Date of Birth Recorded

Yes

Month of Birth is recorded as Year/Month, in the format of yyyymm

Death Recorded

Yes

Patient outcomes are recorded

Availability of death certificate / autopsy information

Other Demographic Data

Yes

Information is available on insured persons or their dependents

Physician & Practioner Info

Physician ID

Yes

However, the data are limited

Physician Specialty

Pharmacy ID

Yes

Diagnoses/Signs & Symptoms

Diagnosis Data

Yes

Diagnoses Coded

ICD-10

Diagnoses: Date Parameters

2010 - Present

Diagnoses: Maximum Number of Codes Allowed

Unlimited

Physical Examination Findings

Yes

Some physical examination data are available from some insurance companies

Birth Defect Data

Yes

Information is available in case there is a congenital abnormality / birth defects

Cancer Data

Yes

Infectious Disease Data

Yes

Environmental Exposures

Yes

Behavioral Data Elements

Yes

Frequency of alcohol consumption, smoking, etc. are all included in the physical examination data.

Procedures

Procedure Data

Yes

Procedures Coded

Receipt code for computerized processing system (MHLW)

Number of Procedures Coded

Unlimited

Procedure Date Parameters

2010 - Present

Laboratory Information

Drug Information

Drug Data

Yes: Prescription only

Drug Date Parameters

2010 - Present

Most data are available since 2012; however, some data are available since 2010.

Drug Regimen & Route

Yes

Route of administration is recorded

Drug Manufacturer

Yes

Drug Dosage

Yes

Drug Days Supply

Yes

Drug Coding System: Maximum Number

Unlimited

Drug Coding System: Primary

Other

[YJ code - YJ codes are part of a drug identification coding system that was developed by the Medical Information System Development Center (MEDIS-DC). It consists of 12 alphanumeric characters: the first four digits represent a drug class effect, the next three digits represent a route of administration, an alphabet represents a dosage form, followed by one digit representing a dosage, two digits representing a brand, and the last digit is a check digit to avoid misreads. The dosage form characters are as follows: A-E: powders, F-L: tablets, M-P: capsules, Q-S: liquids, and T or X: other dosage forms.]

Drug Coding System: Other

ATC-EPhMRA/IPMRG

Drug Generic Name

Yes

Drug Additional Information

Yes

Information on drug prices is available

Biobanks

Biobank Type

N/A

Human Specimen

N/A

Blood Type

N/A

Biomarkers

N/A

Patient ID

N/A

Number of Samples

N/A

Frequency of Sample Collection

N/A

Pre-diagnostic Sample Collection

N/A

Post-treatment Sample Collection

N/A

Method of Sample Collection

N/A

Age at Sample Collection

N/A

Date of Sample Collection

N/A

Reason for Sample Collection

N/A

Method of Sample Storage

N/A

Length of Sample Storage

N/A

Pathology

N/A

DNA Isolation

N/A

RNA Isolation

N/A

Cell Culture

N/A

Genetic Testing

N/A

Access for Research: Specimens

N/A

Access for Research: Genetic Data

N/A

Access for Research: Epidemiologic Data

N/A

Quality Assurance Procedures

N/A

Family History

N/A

Medical History

N/A

Biobank Linkage

N/A

Genetic-PGx Data

Type of Genetic Database

N/A

Source of Genetic Data

N/A

Specimen Genotyped

N/A

Tissue Form

N/A

Genetic Template

N/A

Gene-Drug Response

N/A

Gene-Disease Relationship

N/A

Gene-Health Outcome Relationship

N/A

Gene-Environment Response

N/A

Method of Imputing Genetic Data

N/A

Genetic Variant Identification

N/A

Genetic Data Level

N/A

Genotyping Method

N/A

Method of Genetic Variant Filtering

N/A

Haplotypes

N/A

Haplogroups

N/A

Variable Number of Tandem Repeats (VNTR)

N/A

Single Nucleotide Polymorphisms (SNPs)

N/A

Variant Type

N/A

Variant Class

N/A

Mutation Indicated

N/A

Position

N/A

Amino Acid Change

N/A

Genotype / Polymorphism

N/A

Allele Frequency

N/A

Linkage Disequilibrium (r²)

N/A

Noncarriers Indicated

N/A

Association Statistics

N/A

Genetic Relatedness Pairing

N/A

Data Sharing: Genetic Data

N/A

Access for Research

N/A

Genetic Data Linkage

N/A

Description of Genetic Data Linkage

N/A

Economic Data

Cost Data

Yes

Billing information is available

Cost Denomination

Japanese Yen (JPY)

Type of Cost Data

Yes

Cost of therapy, cost of prescription, cost for medical consultation or doctor visit, etc.

Surrogate Cost Data Link

Description of Surrogate Link

Validation & Linkage

Data Validation Against Original Source

Access to Medical Records

Linkage to Other Databases

Brief Description of Linkage Capabilities

N/A

(Not applicable)

Administrative Information

Database Contact Data

Email: irw-info@intage.com

Website

https://www.intage-realworld.co.jp/service/cross_fact/database_research_en.html

Alternate Contact

N/A

(Not applicable)

Source of Database Funding

Private

(Intage Real World, Inc.)
NOTE: The company changed its name from Japan Medical Information Research Institute Inc. (JMIRI) to INTAGE Real World, Inc. in July 2021.
JMIRI, the retail pharmacy claims database, and Medi-Scope, the health insurance claims database, managed by JMIRI have since been managed and operated under the name, Cross Fact, an integrated healthcare database.

Sponsoring Government Agency

N/A

(Not applicable)

Sponsoring Pharmaceutical Manufacturer

N/A

(Not applicable)

Database Usage Restrictions

Private Access

Data are accessible by companies that have a Japanese branch. These include pharmaceutical companies, academia, and research institutions. For more information re: datasets, please email irw-info@intage.com, and a sales representative will contact you.

Charge for Database Usage

Yes

For cost information, please contact Intage via email at irw-info@intage.com

Data Media Format

Excel / CSV

Aggregated reports (excel, ppt, etc.)
BI (Business Intelligence) software/tool - MotionBoard]

Number of Publications Using Database

References of Studies Using/Describing Database

1. Machida T, Obara T, Miyazaki M, Inoue J, Mano N. Trends in drug prescriptions for type 2 diabetes, hypertension, and dyslipidemia among adults with non-alcoholic fatty liver disease. Ann Hepatol. 2022;27(4):100699.

2. Hozawa S, Maeda S, Kikuchi A, Koinuma M. Exploratory research on asthma exacerbation risk factors using the Japanese claims database and machine learning: a retrospective cohort study. J Asthma. 2022;59(7):1328-1337.

3. Maeda S, Kobayashi S, Takahashi K, Miyata S. Association of comorbidities and medications with risk of asthma exacerbation in pediatric patients: a retrospective study using Japanese claims data. Sci Rep. 2022;12(1):5509.

4. Yokoyama A, Okazaki H, Makita N, Fukui A, Piao Y, Arita Y, Itoh Y, Tashiro N. Regional differences in the incidence of asthma exacerbations in Japan: A heat map analysis of healthcare insurance claims data. Allergol Int. 2022;71(1):47-54.

5. Kubota K, Kelly T, Sato T, Pratt N, Roughead E, Yamaguchi T. A novel weighting method to remove bias from within-subject exposure dependency in case-crossover studies. BMC Med Res Methodol. 2021;21(1):214.

Database Contact

Database Contact Data

Email: irw-info@intage.com

Alternate Contact

N/A

Literature References

References of Studies Using/Describing Database